BoTox Into the Sternocleidomastoid Muscles (SCM)

Purpose

Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms. In this study botulinum toxin will be injected into the SCM to determine if this will result in a temporary slimming effect on the neck and produce a more feminine, youthful neck contour.

Condition

  • Neck Muscle Issue

Eligibility

Eligible Ages
Between 18 Years and 65 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Age eligible individual seeking a more feminine neck appearance

Exclusion Criteria

  • Prior neuromodulator injections in the sternocleidomastoid muscles (SCM) within the past year - Current anticoagulant use - Body mass index (BMI) >30 - Anticipation of significant weight gain or loss during the study period (e.g. patients taking or planning to take within the study period a semaglutide medication.) - Prior allergy to botulinum toxin A - Currently pregnant or breastfeeding

Study Design

Phase
Phase 4
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Botulinum injection into SCM
All participants will receive bilateral botulinum injections into the SCM.
  • Drug: prabotulinumtoxinA-xvfs
    Each participant will receive 60 units (U) of prabotulinumtoxinA-xvfs into each SCM for a total of 120 U. Participants will return in 2 weeks to determine if any touch-up injection is needed.
    Other names:
    • Jeuveau

Recruiting Locations

More Details

Status
Recruiting
Sponsor
Boston Medical Center

Study Contact

Jeffrey Spiegel, MD
617 566-3223
Jeffrey.Spiegel@bmc.org

Detailed Description

The specific study objectives are to determine if: - the neck circumference is decreased at 4 weeks after botulinum toxin (prabotulinumtoxinA-xvfs) injection. - patients can appreciate a difference in their neck contour, self-confidence, and the way they perceive themselves post-injection via an aesthetics outcome and a neck perception survey. - injection of the botulinum toxin into the sternocleidomastoid muscle is safe to perform based on adverse events.