The Longevity Genes in Founder Populations Project
Purpose
We believe extreme longevity is due to specific genes which function to delay aging and prevent disease. The purpose of our research is to identify the genes/mutations associated with healthier aging; to understand the biological functions of these genes/mutations; and to develop therapies to replicate these preservative genetic activities in individuals who do not have the genetic profile for longevity.
Condition
- Extreme Longevity
Eligibility
- Eligible Ages
- Over 65 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Ashkenazi Jewish, age 95+, - Offspring of person age 95+, - Offspring of parents who died age 70 or younger.
Exclusion Criteria
- Non-Ashkenazis
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Case-Control
- Time Perspective
- Prospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| Probands | Ashkenazi Jews ages 95 and older | |
| Offspring | Ashkenazi Jewish offspring of Ashkenazi Jewish parent(s) who lived to at least the age of 95 | |
| Controls | Ashkenazi Jewish people with no family history of longevity |
Recruiting Locations
More Details
- Status
- Recruiting
- Sponsor
- Albert Einstein College of Medicine