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Parents Advancing Toddler Health
Boston University Charles River Campus
Sleep Problem
Behavior, Child
Although early interventions can improve health equity in young children living in poverty,
this promise often is not realized because of barriers to family engagement. The proposed
study will target co-morbid behavior and sleep problems in early childhood, comparing child... expand
Although early interventions can improve health equity in young children living in poverty, this promise often is not realized because of barriers to family engagement. The proposed study will target co-morbid behavior and sleep problems in early childhood, comparing child outcomes and family response to sleep and behavior interventions and investigating the novel strategy of letting families select their intervention.We will enroll 500 low-income toddlers with co-morbid sleep and behavior problems, randomized to 4 parent coaching interventions: sleep, behavior, family choice (sleep or behavior), and an active control. At baseline and at 1, 5, and 9 months post- intervention, we will assess child sleep and behavior and family functioning. We will measure family preference, engagement, and perceived value of each intervention. The goals of the study are: (1) to examine effects of evidence- based sleep and behavior interventions in young low-income children with co-morbid sleep and behavior problems on child sleep and behavior and family functioning; (2) to determine whether parents prefer, engage with, and value a sleep or behavior intervention more; and (3) to examine if giving families a choice of intervention results in higher engagement, higher perceived value and better family and child outcomes than assignment to intervention. By informing best practices for engaging low-income families to treat co-morbid sleep and behavior problems, results will be critical to reducing health disparities for children living in poverty. Type: Interventional Start Date: Mar 2021 |
Photobiomodulation to Improve Cognition in TBI, With fMRI
Boston VA Research Institute, Inc.
Traumatic Brain Injury
Closed Head Injury
Cognitive Dysfunction
The purpose of this small, research study is to examine effectiveness of an at-home
application of an experimental intervention, on thinking and memory in mild-moderate,
closed-head, traumatic brain injury cases. The experimental intervention is light-emitting
diode (LED)... expand
The purpose of this small, research study is to examine effectiveness of an at-home application of an experimental intervention, on thinking and memory in mild-moderate, closed-head, traumatic brain injury cases. The experimental intervention is light-emitting diode (LED) therapy, which is applied to the scalp and through the nose using a head frame device. Participants are expected to complete two, 5-week series of LED treatments, at home, 3 times a week. There will be a 1-month period between the two series. Each home treatment is 20 minutes. Participants will be trained to use the head frame device, in-office. The head frame device falls within the FDA category General Wellness, low-risk devices, and no medical claims are made. A two-hour paper and pencil testing (4 visits) and a one-hour MRI (3 visits) will be administered before and after each treatment series. Participants may be in the study for about 4 months. This study is supported by Vielight, Inc., Hayward, CA/ Toronto, Canada Type: Interventional Start Date: Aug 2019 |
Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women
Tianjin Medical University
Nutritional Requirements
Due to the lack of direct evidence of optimal iodine intake of Chinese children, pregnant and
lactating women and infants were found during the recent revision of Chinese dietary
reference intakes (DRIs) of iodine in 2013 by the applicant Pro. Zhang, and no systematical
research... expand
Due to the lack of direct evidence of optimal iodine intake of Chinese children, pregnant and lactating women and infants were found during the recent revision of Chinese dietary reference intakes (DRIs) of iodine in 2013 by the applicant Pro. Zhang, and no systematical research about compensatory mechanism of iodine nutrition in lactating women was found yet. Previous study funded by United Nations International Children's Emergency Fund (UNICEF) cooperated with the international experts on iodine and key project of national natural science foundation of China under the guidance of Pro. Zhang, had obtained the safe intake range of iodine from children and pregnant women, more than 10 joint papers were published, which laid the foundation of population study and international cooperation. Type: Observational Start Date: Jan 2020 |
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